Focus on Alternative and Complementary Therapies
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Focus Alternat Complement Ther©2005 Pharmaceutical Press
Focus Altern Complement Ther 1997; 2: 185–6
Our earlier data have shown that the water-soluble peat fractions exert an excitatory effect on the spontaneous contractile activity of smooth muscle strips isolated from the guinea-pig stomach. However, there is the question as to what extent the excitation effect is realised through the organic molecules in the water-soluble peat extract.
The spontaneous contraction activity of the smooth muscles were registered by tension transducers under isometric conditions. The present in vitro experiments on smooth-muscle strips from the guinea-pig stomach, used fractions containing chemical compounds with molecular weight between 100 000 - 30 000, 30 000 - 10 000, 10 000 - 3000 and lower than due to organic compounds with molecular weight over 3000 units.
These experiments showed that the excitatory effect was largely due to organic compounds with molecular weight over 3000 units. The fractions containing compounds with molecular weight between 3000 and 10 000 units showed the greatest effect.
Evidence was obtained that when the microelements and the small organic molecules are separated from the water-soluble peat fractions the latter continue to exert their excitatory effect on the spontaneous contractile activity of the guinea-pig gastric smooth muscles.
