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FACT
Focus on Alternative and Complementary Therapies

Action of essential oils in vitro

Lis-Balchin M1, Hart S2
1School of Applied Science, South Bank University, Borough Road, London, SW1 0AA
2Pharmacology Dept., Kings College, Manresa Road, London, SW3 6LX

Objective

Aromatherapy is gaining popularity but scientific evidence for its efficacy is lacking. The effect of essential oils on different muscle systems was therefore investigated.

Materials and methods

Guinea-pig ileum, chick biventer muscle, rat phrenic-nerve-diaphragm and uterus were investigated in vitro. Dilutions of essential oils and components were introduced into a gut bath and the tissue effect monitored through an isometric transducer attached to a pen recorder.

Results

Different essential oils had different effects on different tissues, ie. spasmolytic or spasmogenic. The same essential oil from a different source could also show different effects on the same tissue. The mechanisms of action varied for the different essential oils, though most had a similar non-specific activity.

Conclusion

Due to the diversity of response of different essential oils on different tissues, caution is indicated in the use of essential oils especially in pregnancy and parturition.

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