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FACT
Focus on Alternative and Complementary Therapies

Immunological effects of acupuncture on allergic asthma

Joos S1, Schott C1, Zou Z1, Daniel V2, Martin E1
1Dept of Anaesthetics
2Dept of Immunology, University of Heidelberg, Heidelberg, 69120, Germany

Objective

According to Traditional Chinese Medicine acupuncture is a suitable treatment for complex chronic diseases such as bronchial asthma. We investigated immunological effects of Chinese acupuncture in a randomised, controlled study of patients with allergic asthma.

Materials and methods

The immunological effects of acupuncture treatment given according to the rules of Traditional Chinese Medicine (TCM group, n = 19) were compared with those of a treatment to acupuncture points not specific for asthma (control group, n = 17). All patients were treated 12 times for 30 minutes over 4 weeks. Eosinophils, lymphocyte subpopulations and cytokines in the peripheral blood and the in-vitro lymphocyte proliferation rate were measured before and after acupuncture treatment. All data are means and were tested by the Wilcoxon test.

Results

In the TCM group eosinophils decreased from 4.4% to 3.3% after acupuncture. Within the lymphocyte subpopulations CD3+ (p = 0.005) and CD4+ (p = 0.014) cells increased significantly after acupuncture. There were also significant changes in cytokine concentrations: IL 6 (p = 0.026) and IL-10 (p = 0.001) fell whereas IL-8 rose significantly (p = 0.050). Additionally the in-vitro lymphocyte proliferation rate increased significantly (p = 0.035). In the control group these variables showed no significant changes apart from an increase in CD4+ cells.

Conclusion

These results imply that acupuncture treatment given according to the rules of Traditional Chinese Medicine for allergic asthma has significant modulating effects on the immune systeme.

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