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FACT
Focus on Alternative and Complementary Therapies

How complementary is phytotherapy?

März RW1, Löw D2, Kemper FH3
1Bionorica Arzneimittel GmbH, Kerschensteinerstrasse 11 -15, Neumarkt, D-92318, Germany
2Institut für Klinische Pharmakologie, Johann Wolfgang Goethe Universität, Frankfurt am Main, Germany
3Dir. em., Institut für Pharmakologie und Toxikologie, Westfälische Wilhelms-Universität Münster, Germany

Objectives

Phytomedicines are generally categorised as complementary medicine. This position is analysed.

Methods

A typical textbook of phytotherapy is analysed with respect to the scientific grounds (anatomy, physiology, biochemistry, pharmacology) and compared with a modern textbook of pharmacology.

Results

Thinking in phytotherapy presents no different views regarding site, where phytomedicines act (anatomy, physiology, biochemistry), compared to mainstream medicine. Likewise, the response is regarded as mediated by pharmacological triggers in phytotherapy and in conventional medicine (although these may be unknown for many of the plant medicines). The difference lies on the site of the triggers, not in their materialistic nature as such, but in the number and activities of compounds.

Discussion

Phytotherapy is completely based on materialistic and scientific grounds. The only peculiarity is the complexity of its triggers, which include a broad spectrum of chemical structures with possible pharmacological activities. This difference has implications on pharmacological, but not on clinical research methodology, as efficacy is defined by influence of a treatment on a disease. In fact, several herbal preparations (e.g. Gingko, Hypericum, Vitex, or the combination Sinupret®) were clinically evaluated according to classical clinical research principles.

Conclusions

The question, to which extent phytomedicine is complementary, has to be answered as follows: no need of complementary clinical research strategies except the need of strict pharmacognostic definition of the medicine. In pharmacological research, complexity may pose problems, which can be resolved with sophisticated scientific methods.

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