Effects of herbal mixture on symptoms of stress and mood profiles in high-school girls: a randomised, double-blind, placebo-controlled trial

Lee MS¹, Shin YI², Joo MC², Shin BC³, Moon BS⁴, Shin SH⁴, Moon SR⁵

¹Professional Graduate School of Oriental Medicine, Wonkwang University, Korea

²Department of Physical Medicine & Rehabilitation, Wonkwang University School of Medicine, Korea

³Department of Rehabilitation Medicine, College of Oriental Medicine, Wonkwang University, Korea

⁴Department of Internal Medicine, College of Oriental Medicine, Wonkwang University, Korea

⁵Department of Radiation Oncology, Wonkwang University School of Medicine, Korea

Objective

The aim of this study was to investigate the effects of herbal mixture with Cyperus rotundus L. on symptoms of stress and mood state in a randomised, double-blind, placebo-controlled trial.

Materials and methods

Forty healthy high-school girls volunteered to participate and were randomly assigned to either a herbal mixture group (n = 20) or a placebo control group (n = 20). Subjects consumed the herbal mixture or placebo once a day for 3 days.

Results

Total symptoms of stress and subscales of symptoms of stress decreased significantly and mood state scores increased significantly in the herbal mixture group as compared with the control group.

Conclusion

These results suggest that the herbal mixture with Cyperus rotundus L. is beneficial in alleviating the symptoms of stress and in enhancing mood.

Acknowledgement

This study was supported by grants for the Oriental Medicine R&D projects (03-PJ9-PG6-SO02-0001), Ministry of Health and Welfare, Republic of Korea.

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