Indian researchers assessed the efficacy of an integrated approach of yoga therapy (IAYT) on cognitive abilities in climacteric syndrome. They conducted an RCT wherein the participants were divided into experimental and control groups. One hundred and eight peri-menopausal women between 40 and 55 years with follicle-stimulating hormone level equal to or greater than 15 miu/ml were randomly allocated into the yoga and the control groups. The yoga group practised a module comprising breathing practices, sun salutation and cyclic meditation, whereas the control group practised a set of simple physical exercises, under supervision (1 h/day, 5 days/week for 8 weeks). Assessments were made by vasomotor symptom checklist, six-letter cancellation test (SLCT) for attention and concentration and Punit Govil Intelligence Memory Scale (PGIMS) with 10 subtests. The Wilcoxon test showed significant reduction in hot flushes, night sweats and sleep disturbance in the yoga group, with a trend of significant difference between groups on Mann–Whitney test in night sweats. There was no change within or between groups in the control group. The SLCT score and the PGIMS showed significant improvement in eight of 10 subtests in the yoga group and six of 10 subtests in the control group. The yoga group performed significantly better with higher effect sizes in SLCT and seven tests of PGIMS compared with the control group.